First in Human: The Trials of Building 10


Purchased by Discovery Communications as a completed concept, and debuted on Discovery in August 2017, First in Human provides unprecedented access to Building 10 on the campus of the National Institutes of Health.  The largest hospital in the world devoted solely to research, Building 10 houses our country’s most brilliant scientific minds carrying out some of medicine’s riskiest and most critical research, testing new treatments in people for the very first time.  The three-part series explores the lives of the doctors, researchers, and patients who together make progress possible in this cutting-edge testing ground.

Narrated by Emmy, Golden Globe, and Critics’ Choice winning actor Jim Parsons (“The Big Bang Theory,”  “Hidden Figures”), directed by PGP founder and Emmy winner John Hoffman, and executive produced by Hoffman and Emmy winner Dyllan McGee, the series will introduce the public to a side of public health and healthcare never before seen.  Because the treatments they’re testing are so new and their outcomes are entirely unknown, the doctors leading first in human trials at Building 10 can only partner with patients who have exhausted the options the medical establishment has to offer. This doctor-patient partnership is utterly unique to medicine: live or die, each of these brave “first in human” volunteers immediately become part of medical history. Previous trials in the building led to the development of modern chemotherapy treatments, the first treatments for HIV/AIDS, and the first successful gene therapy.

First in Human is an unprecedented look inside the NIH Clinical Center, the nation’s largest research hospital, where the medicine of tomorrow is made.